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Medicinal Chemistry ::
Key Role:
To design and synthesize novel small organic molecules that can be developed further as medicines for unmet medical needs.
Key Capabilities:
- Strength of 50 skilled medicinal chemists having competence of understanding therapeutic targets and evaluating novelty and patentability of various chemical scaffolds.
- Designing NCEs based on informative data from structural studies and feedback from computational simulation by employing 3D-pharmacophore, structure based virtual screening and QSAR studies.
- Synthesizing NCEs with significant potency, selectivity and safety for specific target proteins/receptors in different therapeutic areas and developing structure-activity relationship (SAR) for lead identification.
- Lead optimization to enhance the ability of NCE to access the therapeutic target in vivo.
- Dedicated team of chemists for scale-up of selected NCEs as well as their process development.
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